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While hGH doesnt directly increase testosterone levels, some studies suggest that it may indirectly affect testosterone by stimulating the release of hormones that regulate testosterone production, says hormone specialist James R

Likewise, higher circulating levels of IGF-1 have been consistently associated with multiple site-specific cancers in epidemiologic studies 12

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Anabolic steroids: a review of their effects on the muscles, of their possible mechanisms of action and of their use in athletics

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They simply lose their ability to bind to GLP-1 receptors effectively