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In addition, nanoemulsions SSB-NMs co-delivered with TGF- inhibitors and selenocysteine (SeC) can effectively inhibit TGF-/TGF- RI/Smad2/3 signaling thereby stimulating the expression of NKC2D on NK92 cells and NKG2DL on tumor cells and significantly improving the lytic capacity of NK92 cells and promoting the immune response (94)

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The researchers used both in vitro cell culture (HaCaT keratinocytes and primary human dermal papilla cells) and in vivo mouse models

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This activation initiates the entire downstream reproductive hormone cascade

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L., Kieviet, L

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