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Anti-inflammantory and antioxidant effects of vitamin A (212, 213), C (214, 215), D (216, 217) and E (213) also involve inhibition of NF-kB as well as activation of Nrf-2 signaling pathways involved in cellular antioxidant response (218, 219)
In the brain, neuronal damage and alteration of cognitive processes occur
The central role of vitamin D in immune regulation and T1D pathogenesis Vitamin D deficiency is a major environmental risk factor that has pleiotropic effects on immune homeostasis and beta cell health
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These genetic insights should be interpreted with a qualified healthcare provider as part of a comprehensive treatment assessment