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Wambebe C: African Indigenous Medical Knowledge and Human Health

(2013, October 28)

3.2.2 Experimental studies and mechanisms of PD Pathological accumulation of metal ions or a rapid increase in monoamine oxidase B (MAO-B) activity can induce endogenous dopamine (DA) oxidation, leading to -synuclein aggregation, mitochondrial dysfunction, and other factors contributing to the heightened incidence of PD

Researchers have observed modulatory effects on brain reward pathways, potentially reducing symptoms of depression, anxiety, and even curbing addictive behaviours such as alcohol or food cravings