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Nutrition, Metabolism and Cardiovascular Diseases, 28 (8), 779786

References Chang, H

Multiple studies have reported that Epithalon administration can extend both mean and maximum lifespan by 10-25% or more compared to control animals - effects approaching those seen with caloric restriction

human efficacy and safety for these uses are not established

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12 Preclinical data also have shown that it rapidly increases mGlu2 receptor expression via histone acetylation, leading to sustained antidepressant-like effects