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This reduces any momentary discomfort and allows the solution to disperse into tissue

Other treatments like insulin [66] or metformin [67,68,69] have shown positive effects

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However, there are situations in which GLP-1 agonists should be discontinued in perioperative care such in cases of acute kidney injury requiring renal replacement therapy and in cases of postoperative ileus (Hurst, et al., 2021)