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GIP is an incretin hormone that indirectly regulates glucagon secretion and increases glucose-stimulated insulin secretion [17]

Additionally, its ability to improve insulin sensitivity and regulate adipose tissue inflammation makes it an attractive candidate for managing metabolic disorders beyond diabetes, such as non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome

Data were evaluated for distribution patterns using tests including Shapiro-Wilk and KolmogorovSmirnov tests and by visual inspection of the distribution residuals

Natural GLP-1 has a very short half-life of approximately 2 to 3 minutes because it is rapidly broken down by the enzyme dipeptidyl peptidase-4 (DPP-4)

While rare complications like gastroparesis (stomach paralysis) or pancreatitis can occur, they are uncommon

Each step up delivers roughly three additional percentage points