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The most meaningful tissue remodeling results are typically visible at the three-month mark and continue to develop for several weeks after the cycle ends

Obesity has become a global public health problem

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These reports are anecdotal and do not constitute clinical evidence

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Samples were fixed in 10% buffered formalin overnight at 4C, dehydrated with increasing concentrations of ethanol, embedded in paraffin, cut into 5 m sections, and stained with hematoxylin and eosin (HE) or Massons Trichrome Stain Kit (Sigma-Aldrich)