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In diseases linked to FAD deficiency or disrupted riboflavin metabolism, like L-2-HGA and AIFM1-related encephalopathy, aberrant chromatin states and DNA methylation patterns have been observed, underscoring a tight connection between riboflavin availability and gene expression regulation

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Clin Exp Immunol 209(2):161174 Shahid M, Ashraf M, Sharma S (2024) "Physiology, thyroid hormone 2023." StatPearls

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