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2.1.2 Disruption of pulmonary epithelial barrier functions The epithelial layer forms a crucial physical barrier in the intestinal, respiratory, and skin tissues, which play a pivotal role in maintaining tissue homeostasis, immune response, and protecting the body from pathogens

The ability to target liver inflammation while reversing the driving metabolic dysfunction (adiposity) positions GLP-1 RAs (and emerging dual/triple agonists like Tirzepatide and Retatrutide) as the cornerstone of future management

It is primarily synthesized in the liver and serves multiple vital functions, including: Antioxidant Defense : Glutathione neutralizes free radicals and prevents oxidative stress, which can lead to cellular damage

[DOI] [PMC free article] [PubMed] [Google Scholar] 76.Shi M.H., Wu Y., Li L., Cai Y.F., Liu M., Gao X.H., Chen H.D

Neuroprotection: Exploring its potential to mitigate damage from traumatic brain injury or protect dopaminergic neurons in models of Parkinson's disease

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