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Repositioning lidocaine as an anticancer drug: the role beyond anesthesia

17(12): CR677CR682.

In its reduced form, it can combat free radicals by transferring an electron to them

have observed that HIF is highly active under hypoxic conditions and promotes the transcription of the target gene ITGA6 , which, in conjunction with other integrins, is enriched in breast stem cells and promotes the acquisition of MDR phenotypes in breast cancer 48

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