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AstraZeneca and Teva similarly stood firm

Although the complex remains highly dynamic upon binding, we were able to obtain a set of distance restraints from these experiments

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Oxyhemoglobin suffers autoxidation daily (23%), with oxidation of heme ferrous iron into ferric iron [10], leading to the formation of methemoglobin (metHb), which is not capable of O 2 transport, and the release of superoxide anion that is converted to H 2 O 2 , with a lower oxidant capacity [11]

The word "idiopathic" means that we don't know the cause