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The most frequently reported clinical outcomes included initial hospitalization or prolonged hospitalization (13.6%) and other serious medical events (12.3%)

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Per the website, the average person loses about 20.6 pounds, and about 8.6 years off their metabolic age after the first 90 days

These transcriptional effects of SREBP include (but are not limited to) increased expression of glucokinase (encoded by GCK), liver pyruvate kinase (encoded by PKLR), lipoprotein lipase (encoded by LPL), fatty acid synthase (encoded by FASN), and acetyl-CoA carboxylase 1 (encoded by ACACA), and decreased expression of glucose 6-phosphatase (encoded by the G6PC gene), fructose 1,6-bisphosphatase (encoded by FBP1), and mitochondrial phosphoenolpyruvate carboxykinase (encoded by PCK2)

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