The intracellular concentrations of vitamin B12 can be inferred through the total plasma concentration of homocysteine, which can be converted to methionine through an enzymatic reaction that uses 5-methyltetrahydrofolate as the methyl donor group
International Journal of Biological Macromolecules, 86: 362375 Boogaerts T, Quireyns M, de Loof H, Bertels X, van Wichelen N, Pussig B, Saevels J, Lahousse L, Bonmariage P, Hamelinck W, et al
If the patients concern involves growth hormone or IGF-1 signaling, body composition, or another endocrine issue, the evaluation is different again
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