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The Journal of experimental medicine
Dulaglutide (Trulicity), liraglutide (Victoza), and exenatide (Byetta, Bydureon) work through similar mechanisms but have different pharmacokinetic profiles
Mice were switched to a HFD with 400 mg/kg diet tamoxifen citrate (Envigo, TD.170935) for the duration of the study in order to induce GLP-1R knockdown
As a research reference standard it is used to investigate angiogenesis, fibroblast migration, and tendon-to-bone healing kinetics in cell-culture and rodent models
As a result, less iron becomes available for red blood cell production, contributing to anemia of chronic disease