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Disclaimer: This information reflects findings from preclinical and observational research

The research utilized male Sprague-Dawley rats and various in vitro and ex vivo experimental models

[Abstract] The levels of IL-1, TNF-, and IL-10 in the brain were investigated by ELISA in Dihexa-treated (1.44 mg/kg and 2.88 mg/kg) APP/PS1 mice

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In vitro functional analyses confirmed their mature hepatocyte characteristics: they showed high transcription and protein expression of ALB, A1AT, CYP3A4, and CYP2C9, comparable to primary human hepatocytes (PHs)

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