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endocrine-axis modeling in animal systems as a receptor-selective pharmacology tool compound

The formulation and delivery of SFN present additional hurdles

Bottom line: Employment drug testing won't detect peptides

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Thus, considering dose response of APAP in future study designs will be crucial in improving the mechanistic understanding of the differences between spontaneous transplant-free survival versus transplant-assisted survival and ALF-related deaths observed in APAP overdose patients