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Systemic toxicity-collectively termed local anesthetic systemic toxicity (LAST)-necessitates prompt airway control, seizure suppression with benzodiazepines, and lipid emulsion therapy, which sequesters lipophilic drug molecules and improves hemodynamic stability
corroborated by Silverii 2025 RCT meta-analysis (OR 1.55) on a small absolute base
Consider a researcher who needs a 4mg weekly dose
B12 is also a key player in energy metabolism, as it helps the body convert food into glucose, which is then used as fuel by the body
Hydration, nutrition, sleep, and stress management all influence both results and side effects