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In addition, administration of GLP-1RAs in experimental stroke was found to activate several intracellular signaling pathways involved in neuroprotection, including cyclic adenosine monophosphate (cAMP)/PKA/cAMP-response element binding protein (CREB)

Some patients may experience mild fatigue or low energy , especially when starting treatment

Perturbation in its signaling early in life has been associated with several neuropsychiatric disorders [215, 216]

Source: Nature Medicine, American Society of Nephrology Author Affiliations: University Medical Center Groningen

Subgroup analyses by sex and age showed consistent results

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