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While current limited evidence does not suggest these medications directly worsen Crohn's disease activity, their gastrointestinal effects require thoughtful management

Liposomal versions cost more, though, so it's a genuine trade-off between absorption and budget

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Mol Cell Biochem 477:19872000

However, this does not equate to unaffected performance

In primary mouse chondrocytes, treatment with liraglutide reduced the mRNA expression of iNOS, MMP-13 and ADAMTS5 , thus leading to reduced secretion of a battery of inflammatory markers such as NO, prostaglandin E 2 , and IL-6 [17]