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Moreover, nuclear factor erythroid 2 related factor 2 (Nrf2) is a significant regulator of redox balance that controls both proinflammatory and anti-inflammatory effects, but its detailed mechanism remains unknown
The dried samples were mixed with 500L of phosphate buffer prepared in D 2 O (pH 7.40 0.05), containing 3-trimethylsilyl-[2, 2, 3, 3, - 2 H 4 ]-propionate (TSP) at a final concentration of 0.33 mM, and then transferred to 5 mm NMR tubes
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The agency also notes possible risks related to immune reactions, peptide-related impurities, and difficulties in fully characterizing the active pharmaceutical ingredient
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