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Nrf2/ARE-dependent genes code for numerous mediators of the antioxidant response, including GCL, glutathione S-transferases (GSTs), thioredoxin, NAD(P)H quinone oxidoreductase 1 (NQO-1), and heme oxygenase 1 (HO-1) (21)

Heat shock response inhibits nf-b activation and cytokine production in murine kupffer cells

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Researchers in this category commonly compare receptor selectivity, agonist families, concentration-response models, and stability across related incretin or amylin-pathway compounds

If levels of glutathione are low, the levels of free radicals increase

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