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Sikiric et al., 2020a

Alternating between them disrupts this titration schedule, potentially causing dose-stacking effects where residual drug from one agent combines unexpectedly with a new one, triggering severe nausea, vomiting, or dehydration

Exendin-4 induces a novel extended effect of ischemic tolerance via crosstalk with Igf-1r

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One particularly common medication in this realm is Wegovy, which has gained attention for its effectiveness in aiding weight loss