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49 Furthermore, molecular signaling pathways play a critical role in the response of ACL tissue to mechanical stress and injury

While these findings are intriguing, the leap from controlled laboratory settings to the complex biological environment of the human body is significant and uncertain

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The special and temporal regulation of Wnt/-catenin, TGF, FGF, BMP, and HGF as well as the liver-specific transcription factors including FOXA and HNFs are crucial in liver development

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