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In 39 randomized double-blind, placebo-controlled (RDP) human clinical trials including 2,009 subjects, Pycnogenol French maritime pine bark extract supplementation for two weeks to six months has been shown to beneficially affect cardiovascular health, chronic venous insufficiency, cognition, joint health, skin health, eye health, womens health, respiratory health and allergies, oral health and sports performance

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D-CuP exhibited multivalency, significantly enhancing biological activity and stability against proteases

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Most clients experience nothing more than a brief moment of discomfort at the injection site, which passes within seconds