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10.1074/jbc.M007597200 132 ShivakumarA.Yogendra KumarM

Its simultaneous activation of three receptor pathways GLP-1R for appetite suppression and insulin secretion, GIPR for augmented insulin response and central appetite modulation, and GCGR for energy expenditure and hepatic fat mobilisation produces metabolic effects that exceed what single or dual agonism can achieve [4][8][9]

Exp Gerontol 2003

Likewise, through the amelioration of testicular oxidative stress status, enhancement of steroidogenic enzyme activity, and elevation of StAR gene expression, nano LC mitigated CYP-induced decline in testicular hormone levels 98

[3] Medical uses [edit] In the European Union, afamelanotide is indicated for the prevention of phototoxicity in adults with erythropoietic protoporphyria

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