Notably, although there was not a statistically significant increase in biliary disease among GLP-1 receptor agonist users in this study, the FDA 2 added warnings and precautions about acute cholecystitis and biliary disease to the label in late 2022 based on data from placebo-controlled RCTs as well as other observational data 3
NHS access began in specialist weight management services from June 2025 for the highest-need patients, with tirzepatide prescribing incorporated into the GP Quality and Outcomes Framework from April 2026
Chen Z, Bozec A, Ramming A, Schett G
Setting realistic weight loss goals It is important to be realistic about how to achieve your weight loss goals and understand that you will only be able to lose a certain amount of weight
Ozempic is an injectable prescription drug
Semaglutide weight loss timeline Depending on the duration it takes to show visible improvements, the timeline of Semaglutide results can be classified into: Short-term results: Earliest effects are often rapid, beginning within the first 1-4 weeks of treatment