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Randomized, double-blind, placebo-controlled trial of the once-daily GLP-1 receptor agonist lixisenatide in Asian patients with type 2 diabetes insufficiently controlled on basal insulin with or without a sulfonylurea (GetGoal-L-Asia)

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mejora el control de la glicemia, incluso en pacientes que no bajan de peso, efecto que aparece en una etapa temprana del tratamiento, mucho antes de que se alcance la mxima prdida de peso

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Thus, therapeutic monitoring of methotrexate, encouraging its excretion and pharmacological opposition of its nephrotoxicity, is of great importance [47, 48]

Furthermore, a significant reduction in major adverse cardiovascular events (MACE) rates was observed with SC semaglutide compared to placebo [15]