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New sleep problems at 7.5-10 mg often relate to the accelerated weight loss and hormonal changes rather than increased GI effects, which the body has usually adapted to by this point

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Tirzepatide May Be a Lifelong Drug If you stop the medication, you regain the weight theres no question that will happen, says coauthor Louis Aronne, MD, a professor of metabolic research and director of the Center for Weight Management and Metabolic Clinical Research at Weill Cornell Medicine in New York City