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Its important to note that the participants were enrolled in the 52-week extension phase from September 2019 to April 2020

Kim KE, Park I, Kim J, Kang MG, Choi WG, Shin H, Kim JS, Rhee HW, Suh JM

Since CPP-CAND was designed to interfere with the FOXO4-p53 interaction, we investigated the disruption of FOXO4-p53bp1 foci in the nucleus of senescent cells after CPP-CAND treatment

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Total semaglutide used during this phase: 4.0 mg (4 injections of 1.0 mg) Cumulative total through week 12: 7.0 mg At this point, your first 10mg vial is approximately 70% used (7.0 mg of 10 mg)