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Some of the benefits, too, may be explained by the fact that people taking the drugs tend to lose weight, rather than the drugs themselves having a direct positive effect on a particular system or organ

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While the research on effects of long-term use, especially in otherwise healthy individuals, has been ongoing, the current standard protocol is to slowly wean patients off the drug once the desired weight has been obtained

Dong H, Xia Y, Jin S, Xue C, Wang Y, Hu R, et al

After 12 weeks, the MindBody GLP-1 System produced GLP-1 increases of over 200% on average , participants lost up to 25 lbs , and 95% reported reduced sugar cravings

PMID 30195966