Neonatal complete generalized glucocorticoid resistance and growth hormone deficiency caused by a novel homozygous mutation in Helix 12 of the ligand binding domain of the glucocorticoid receptor gene (NR3C1)
The ventral-anterior edge of the VOI was aligned parallel to the genu of the corpus callosum, ensuring avoidance of cerebrospinal fluid (CSF) signal inclusion, consistent with prior research methodologies
Since it is hard to obtain clinical samples in overdose cases that control the many genetic and environmental variables that can affect protein expression, it is often easier to discover proteomics biomarkers in nonclinical toxicity studies and then set up clinical sample collection strategies to further evaluate the potential toxicity biomarkers
This could be because the former consume more of these mushrooms
However, preclinical data does not guarantee human safety
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