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A small controlled human study did not identify a significant effect on stimulated ACTH or cortisol release

Papadia S, Soriano FX, Lveill F, Martel MA, Dakin KA, Hansen HH, et al

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A salt-form theory may be chemically plausible

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Sample type considerations Different biological matrices have different detection characteristics: Urine: Most common testing matrix, metabolites accumulate Blood/plasma: Shorter detection windows for most peptides Dried blood spots: Emerging method with good sensitivity Hair: Not commonly used for peptides but theoretically possible Most anti-doping testing uses urine