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James et al ., 2005, "The SCOUT study: risk-benefit profile of sibutramine in overweight high-risk cardiovascular patients"

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Diarrhea is most common when starting Ozempic or increasing the dose, and it usually improves within a few weeks

Surprisingly, despite increasing Gcg mRNA, chronic IL-6 treatment does not increase plasma GLP-2 levels suggesting a difference in GLP-1 and GLP-2 transcript or protein stability