How may GIP enhance the therapeutic efficacy of GLP-1
On Wednesday it was announced Ozempic and Saxenda will be reviewed in the UK after reports of suicidal or self-harming thoughts among patients.
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Signs of low blood sugarsuch as shakiness, sweating, or confusionshould also be watched for, especially if using other diabetes medicines
Patients who want a non-GLP-1 option: Some patients cannot tolerate GLP-1 side effects such as nausea and GI disturbance
Farina AR, Cappabianca L, DeSantis G, Di Ianni N, Ruggeri P, Ragone M, Merolle S, Tonissen KF, Gulino A, Mackay AR (2011) Thioredoxin stimulates MMP-9 expression, de-regulates the MMP-9/TIMP-1 equilibrium and promotes MMP-9 dependent invasion in human MDA-MB-231 breast cancer cells