If you experience troublesome symptoms whilst taking self-initiated B12 supplements, temporarily discontinuing them whilst awaiting GP review is reasonable
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Elevated temperatures accelerate all chemical reaction rates, including hydrolysis and oxidation
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Sci Rep 5:8610 Thomson M, Liu Y, Nunta K, Cheyne A, Fernandes N, Williams R, Garza-Garcia A, Larrouy-Maumus G (2022) Expression of a novel mycobacterial phosphodiesterase successfully lowers cAMP levels resulting in reduced tolerance to cell walltargeting antimicrobials
A note on whole body wellness