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Decreased GSH levels in some organelles and tissues during aging expose cells to an increased risk of succumbing to stress

The continuous hyperglycemia can induce target organ damage (TOD) by increasing the risk of panvascular disease, including microvascular disease (such as diabetic retinopathy, nephropathy and neuropathy), and atherosclerotic macrovascular disease (cardiovascular, cerebrovascular, and other peripheral vascular diseases)

The review confirmed that animal and human studies demonstrate adequate protein nutrition is crucial for maintenance of GSH homeostasis, and that enteral or parenteral cystine, methionine, N-acetyl-cysteine, and L-2-oxothiazolidine-4-carboxylate are effective cysteine precursors for tissue GSH synthesis

If youre a competitive athlete, note that both peptides are prohibited under the WADA Prohibited List as unapproved substances (category S0)

Arginase Bypass - L-citrulline isn't affected by the enzyme arginase , which breaks down L-arginine in the gut and liver

That said, it always pays to err on the side of caution and I wouldn't use out of date ones in somebody else, unless I had no option