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SFN mitigates TNF-a and IL-22-induced activation of inflammatory pathways and proliferation in HaCaT cells IL-22 is known to bind to the IL-22 receptor on keratinocytes, induce STAT3 phosphorylation, and promote keratinocyte proliferation [25, 26]

The reconstituted solution remains stable for approximately 30 days under proper refrigeration

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BSO treatment decreased intracellular GSH levels from 40 to 0.8 nmol/10 6 cells, and further decreased below detection limits following QI exposure (data not shown)

J Gastroenterol Hepatol 2008;23:70715

Takotsubo syndrome associated with structural brain alterations of the limbic system