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Medically reviewed by Alan Lucks | MD , Alan Lucks MDPC Private Practice - New York on January 6th, 2026

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This pathway has been suggested to increase heart rate under certain conditions (e.g., stress), as both activation of brainstem GLP-1 neurons and direct application of GLP-1 onto the spinal cord elicit tachycardia 21

It mimics the action of a natural hormone called GLP-1 (glucagon-like peptide-1), which helps regulate blood sugar levels and appetite

Formally placing the substances on FDA's list of drugs that are safe for compounding would require new regulations, which can take months or years to draft