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The combination creates a more robust GLP-1 signal than either approach alone, which translates to better appetite control, better insulin secretion, and better blood sugar management

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Unlike prescription GLP-1 medications, which can cause side effects like nausea, vomiting, and in rare cases, more serious issues, natural approaches typically come with fewer adverse effects

The GLP-1R are expressed in tissues other than pancreatic islets 24 , as in hepatocytes, but studies suggest that certain actions of GLP-1 in hepatic glucose metabolism occur through mechanisms that are independent of GLP-1R, and no alternative route seems to have been fully elucidated 25