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Experiments with Nrf2-deficient mice revealed that elevated Nrf2 promoted phosphorylation of AKT, confirming thus the interference between Nrf2 and PI3K/AKT pathways resulting in increased anabolic pathways in metabolic reprogramming (Mitsuishi et al

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3.1.2 Metabolism and excretion of Hydroxytyrosol Following absorption, HTY undergoes rapid and extensive metabolism, primarily through glucuronidation and sulfation pathways in the intestine and liver [38, 39]

After reconstitution, store at 2-8C and use within 21 days

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