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Currently, the identification of flavonoid compounds has exceeded 10, 000, with the figure continuing to increase (19)

Ottridge R, Mollan SP, Botfield H, Frew E, Ives NJ, Matthews T, Mitchell J, Rick C, Singhal R, Woolley R, Sinclair AJ

In clinical practice, it is valued for helping reduce oxidative stress, support detoxification pathways, and gradually improve overall skin clarity when used in structured IV or IM protocols

While toxicity is rare, excessive intake of certain B vitamins (particularly B or B) from multiple sources could increase the risk of side effects (like niacin flush or peripheral neuropathy)

In contrast, resmetirom (Rezdiffra) received FDA approval in 2024 specifically for noncirrhotic NASH with F2F3 fibrosis

Additionally, NSAIDs can affect kidney function by reducing renal blood flow, particularly in patients with pre-existing kidney disease, dehydration, or those taking other medications that stress the kidneys