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Tengholm, A., & Gylfe, E

By binding with eIF4A, Pdcd4 inhibits eIF4A RNA helicase activity and thereby suppresses translation

The requirement of two distinct glutathione interaction sites for the efficient reduction of GSSR by GSH explains the deviating properties and substrate preferences of glutaredoxin subfamilies as well as thioredoxins with implications for the design and optimization of artificial enzymes and inhibitors