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PMID: 17077328

Our results showed that hunger-free fasting was able to reduce -GGT concentrations to a greater extent than modified fasting

The glutaredoxin catalytic mechanism depends on the GSH/GSSG ratio

The enhanced expression of MdesGST-1 (Delta group) in the midgut and fat body of Hessian fly larvae might explain its involvement in the detoxification of plant defense compounds such as flavonoids and scavenging endogenous ROS

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Olaparib, for instance, is an FDA-approved inhibitor of the enzyme poly ADP ribose polymerase (PARP) which can efficiently kill BRCA mutant tumor cells, a successful synthetic lethality based targeting strategy used in breast cancers and ovarian cancers (165)