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People must seek treatment if they cannot stop on their own

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5.1 Major Weight Loss Trials (Semaglutide) The STEP (Semaglutide Treatment Effect in People with obesity) programme demonstrated substantial weight reduction with once-weekly semaglutide. Key findings: Mean weight loss of ~15% body weight Reduced caloric intake Gastrointestinal side effects most common during dose escalation Micronutrient levels were not systematically reported as primary outcomes

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Why brand and generic names both exist The active ingredient, also called the generic or nonproprietary name, identifies what is chemically inside the pen or tablet