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Within enterocytes, carotenoids may be enzymatically cleaved by -carotene-15,15-oxygenase or -carotene-9,10-oxygenase to generate bioactive metabolites

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In muscle, Akt phosphorylation leads to mTOR activation and suppression of atrophy genes

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When EPA alone was administered, significant increases in fatty acids derived from EPA, DHA and DPA, and significant decreases in stearate and arachidonate (20:4n-6) were observed (Table 3)