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Laboratory research has examined its interaction with nitric oxide (NO) pathways, growth factor modulation including VEGF and EGF, and the FAK-paxillin signaling cascade used in tissue remodeling studies

Marketed under brand names including Ozempic, Wegovy, and Rybelsus, this medication works by mimicking the action of naturally occurring GLP-1 hormone

Recent investigations confirm that multi-receptor agonism (tirzepatide) significantly upregulates the BDNF-TrkB axis through CREB activation, providing robust protection against neurodegeneration [40]

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Diets high in refined carbohydrates and low in protein or fiber can cause blood glucose fluctuations that trigger hunger signals despite adequate caloric intake

10.1016/j.freeradbiomed.2018.03.004 19