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Whether DMTs can slow disability worsening in older people with MS and late-onset MS is unclear

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doi: 10.1194/jlr.D004077

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Additionally, hydrogen's small molecular size allows it to reach cellular compartments inaccessible to larger antioxidant molecules, providing protection to mitochondria and nuclei without requiring metabolic processing for elimination

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Berberine is a relatively large molecule that is poorly absorbed even orally - which is why oral supplements typically require multiple daily doses

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