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Despite promising preclinical studies, a 12-week clinical trial using an iteration of this initial dual-incretin agonist failed to demonstrate superiority relative to a GLP-1R monoagonist 15 , raising questions about multi-receptor strategies in humans

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A new study in mice and humans suggests GLP-1 medicines drive weight loss primarily by reducing fat, while preserving muscle function and easing fears about harmful muscle wasting

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My 10-year-long debilitating fatigue was lifted practically overnight, and I went from sleeping for 11 to 12 hours per night, to 8 hours just because I started digesting my food better