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Glutathione is also the obligate substrate for glutathione S-transferases (GSTs), the enzyme family responsible for phase II hepatic detoxification conjugating GSH to electrophilic xenobiotics, heavy metals, and endogenous toxins to render them water-soluble and excretable
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GPx1 knockdown suppresses chondrogenic differentiation of ATDC5 cells through induction of reductive stress
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